From Delta blues to beachside views, Mississippi is brimming with unforgettable spots for a girls’ getaway. Whether you’re sipping cocktails on the Gulf Coast, exploring artsy towns, indulging in soulful Southern cuisine, or unwinding at a luxe spa, the Magnolia State delivers charm, culture, and plenty of opportunities to laugh, relax, and make memories with your favorite people.
Natchez, MS
In Natchez, history, elegance, and Southern charm come together for an unforgettable girlfriends’ getaway. Perched high on the bluffs of the Mississippi River, this storied city invites you to slow down and savor its beauty. Start your visit with a tour of the town’s famed mansions — many of which are open year-round for immersive peeks into the past. Spring and fall’s Natchez Pilgrimage offers extra magic with costumed guides and blooming gardens.
Shopping is a delight in Natchez’s walkable downtown, filled with locally owned boutiques, antique stores, and artisan shops where you can uncover everything from statement jewelry to Southern home decor. After some retail therapy, indulge in the local dining scene. Favorites include Magnolia Grill for river views and Southern classics, and The Camp Restaurant for craft beer and elevated pub fare.
Pamper yourselves at one of Natchez’s day spas with a massage, facial, or mani-pedi before enjoying sunset cocktails along the river. In the evening, take in live music at a cozy venue or try your luck at the Magnolia Bluffs Casino.
With its blend of history, hospitality, and modern indulgences, Natchez offers the perfect mix of culture, relaxation, and fun, making it an ideal base for your next girlfriends’ escape.
Starkville, MS
Starkville, Mississippi, offers the perfect mix of flavor, fun, and small-town charm for a girlfriends’ getaway. Foodies will love dining at The Older Brother for inventive dishes, indulging in authentic Italian fare at TASTE Italian Kitchen, or pairing small plates with fine wine at L’Uva Wine Room. When it’s time for drinks, the options are just as diverse. Sip craft cocktails at The Landing, kick back with tropical vibes at Hobie’s Tiki Dawgs & Drinks, or toast the night at The Ice House.
Shopping is a must in Starkville, with locally loved spots like The Olive Tree, VACE, Medora, and Mississippi EyeWear offering everything from stylish apparel to unique gifts. Between stops, explore the city’s public art murals or take a music history detour to the Johnny Cash Country Music Trail Marker. You can even see his room at the Far Out Motel!
Pamper yourselves at a local spa or salon, catch a show at the Starkville Community Theatre, or immerse yourselves in nature at the Noxubee National Wildlife Refuge. For a playful twist, hit the pickleball courts or cool off at McKee Park’s splash pad. Starkville delivers big on experiences, making it an ideal spot for memory-making with your best friends.
Cleveland, MS
Looking for a girls’ getaway that blends culture, cuisine, and charm? Cleveland, Mississippi, delivers all that and more. Named one of the South’s best small towns by Smithsonian Magazine, it’s home to the GRAMMY Museum Mississippi, where 28,000 square feet of exhibits celebrate music legends across genres.
Cleveland’s culinary scene is equally impressive. Don’t miss Leña Pizza and Bagels, named one of The New York Times’s top 22 pizzerias in the U.S. Downtown is filled with acclaimed restaurants, perfect for catching up over cocktails and shared plates.
Shop the Crosstie District, known for its early 20th-century charm, delightful boutiques, and antique stores. If you visit mid-November through New Year’s Eve, catch the 50 Nights of Lights, a dazzling holiday display with over a million lights, night markets, and festive caroling.
Stay in style at the Cotton House or the Lyric West End, both offering upscale accommodations, restaurants, and Southern hospitality. With live music five nights a week at area restaurants, the vibe is always right for a girls’ night out.
Round out your trip with a visit to McCarty’s Pottery and Peter’s Pottery or soak in blues history at Dockery Farms. For connection, culture, and comfort, Cleveland makes the perfect girlfriend getaway.
Ridgeland, MS
Ridgeland offers an ideal blend of indulgence and small-town charm, perfect for a girlfriends’ escape.
Start your day with a serene spa experience in the walkable Railroad District, where local wellness studios offer treatments of all kinds — massages, facials, and more. Afterward, head to CW Organics Apothecaire & Tea Room for high tea, where organic teas, delicate pastries, and beautiful ambiance set the scene for great conversation and a touch of luxury.
Shopping lovers will find their happy place along the Retail Trail at Renaissance at Colony Park. This open-air lifestyle center features high-end boutiques, national brands, and stylish local shops — all set among lush landscaping and beautiful architecture.
As the sun sets, hop on Ridgeland’s Cocktail & Mocktail Trail. With creative drinks crafted at various restaurants and bars around town, there’s something for everyone —whether you’re sipping something spirited or alcohol-free.
Wrap up the day with dinner at TASTE Italian Kitchen, a favorite for its cozy atmosphere and authentic dishes like handmade pasta and wood-fired pizza.
Whether you’re unwinding at the spa, sipping tea in style, or toasting to friendship and great memories, Ridgeland offers a perfect mix of relaxation, retail therapy, and memorable meals.
Tupelo, MS
Tupelo, Mississippi is the place for a girlfriends’ getaway filled with flavor, fun, and a dash of rock ’n’ roll history.
Start with a tasting (or a frozen slushie!) at Queen’s Reward Meadery, where handcrafted mead made with 100% Mississippi honey offers a unique twist on happy hour. Then, get your retail fix across Tupelo’s three distinct shopping districts — Downtown, Midtown, and Barnes Crossing — each offering its own charm, from stylish boutiques to artisan goods.
For brunch or lunch, don’t miss CharCutie Tupelo, known for its grazing boards and cozy vibe. When dinnertime rolls around, indulge at local favorites like Forklift, Park Heights, or Jobos, where creative Southern cuisine meets a vibrant atmosphere.
Balance all that indulgence with a little wellness at Haven Studio, offering spa services, yoga, and pilates in a serene, modern space. Then dive into the city’s arts and culture scene at Caron Gallery or the GumTree Museum of Art.
No trip to Tupelo is complete without a stop at the Elvis Presley Birthplace and Museum to honor the King of Rock ‘n’ Roll. Cap it all off with live music and an eclectic bar scene at Blue Canoe, and you’ve got the perfect mix of memory-making moments and girl-time magic. Plan your getaway and imagine what you can do here!
Vicksburg, MS
Vicksburg is where Southern charm meets riverside luxury — an ideal setting for an unforgettable girlfriends’ getaway. Start with a stay at one of the city’s elegant accommodations, such as Anchuca Historic Mansion & Inn, Duff Green Mansion, or the Mulberry Hotel, each offering comfort, style, and a dose of history.
By day, explore Vicksburg’s vibrant shopping scene. Stroll through downtown boutiques for chic apparel, unique jewelry, and locally crafted art. When it’s time to relax, Vicksburg offers a variety of spas and salons ready to treat you to soothing massages, rejuvenating facials, and other indulgent treatments.
Dining in Vicksburg is a treat, with options like 10 South Rooftop Bar & Grill for sweeping Mississippi River views or Walnut Hills for classic Southern fare. For a touch of glamour, sip a cocktail beneath the sparkling centerpiece at Cedar Grove Mansion’s chandelier bar.
As the sun sets, the city comes alive with nightlife. Try your luck at one of the casinos, enjoy live music at local venues, or wander the streets to find murals and public art that add a creative pulse to the riverfront.
With its blend of luxury, culture, and entertainment, Vicksburg delivers the perfect balance of relaxation and excitement for your next girlfriends’ escape.
Corinth, MS
Corinth, MS, is a charming destination where history, shopping, and quirky culinary traditions come together for a memorable getaway. Known as the “Crossroads of the South,” Corinth played a vital role in the Civil War, with key sites like the Corinth Civil War Interpretive Center and historic downtown landmarks telling the story of the area’s significance during that era. History buffs will love walking the same streets where soldiers once marched.
Beyond its significance in Civil War-era history, Corinth is also renowned for a beloved local dish — the Slugburger. Originally a Depression-era delicacy made from a blend of beef and soy meal, deep-fried to crispy perfection, it is still wildly popular today. In fact, the Slugburger inspired its very own annual festival. No trip to Corinth is complete without trying one.
After lunch, stroll through downtown Corinth’s charming boutiques and antique shops. You’ll find an eclectic mix of locally owned stores offering everything from vintage treasures and home decor to clothing and accessories.
Whether you’re savoring a Slugburger, uncovering history, or treasure hunting at local shops, Corinth offers a welcoming blend of small-town charm and unique experiences. It’s the perfect spot for a girlfriend getaway filled with stories, shopping bags, and a taste of true Mississippi flavor.
Laurel + Jones County, MS
Laurel and Jones County offer a Southern gem tailor-made for girlfriend getaways. Downtown is a walkable district is brimming with locally owned boutiques, perfect for browsing with coffee in hand and discovering one-of-a-kind treasures. Don’t miss Laurel Mercantile Co. and the Scent Library (made famous by HGTV’s Home Town), along with Guild & Gentry for a sweetie-worthy souvenir, and Southern Antique Gift Mall and Hand+Made for Mississippi-made goods.
Add a splash of culture with a visit to the Lauren Rogers Museum of Art, the state’s oldest art museum, offering impressive collections and rotating exhibits. You can also book a private jewelry class through local maker Novi, or explore the vibrant mural trail weaving through downtown and beyond.
For a truly unique stay, The Lodge at Sweetwater Studios offers adult-only glamping and creative retreats nestled in nature. It’s designed for yoga lovers, artists, and anyone needing a peaceful reset. Prefer staying in town? Laurel’s cozy short-term rentals, including historic cottages and featured homes, are ideal for wine nights and heart-to-hearts.
Whether you’re mural-spotting, antique-hunting, or just soaking in the small-town charm, Laurel and Jones County deliver the perfect mix of relaxation, creativity, and connection — making the area a top pick for your next girlfriends’ escape.
This article is sponsored by Visit Natchez, Visit Starkville, Visit Cleveland MS, Explore Ridgeland, Tupelo Convention and Visitors Bureau, Visit Vicksburg, Visit Corinth, Visit Laurel + Jones County, and Visit Mississippi.
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